Endocrine Abstracts

Purpose: Transsphenoidal endoscopic surgery (TSS) is the first-line treatment for Cushing’s disease (CD). Persistence and recurrence of hypercortisolism after TSS considered important problem. In this case search for CD remission predictors is actual.Aim: To study the role of preoperative oral high-dose dexamethasone suppression test (HDDST) in the prognosis of CD remission after TSS.Materials and methods: 60 patients with Cus...

Purpose: Transsphenoidal endoscopic surgery (TSS) is the first-line treatment for Cushing’s disease (CD). However, persistence and recurrence of hypercortisolism after TSS considered important problem. In this case search for CD remission predictors is actual.Aim: To study the role of preoperative oral high-dose dexamethasone suppression test (HDDST) and pituitary MRI in the prognosis of CD remission after TSS.Materials and me...

Introduction: Persistence after transsphenoidal surgery remain a significant challenge in management of acromegaly. Value of basal growth hormone (GH) evaluation in early postoperative period as marker of acromegaly persistence has been proposed and discussed in the literature, but is not widely used in clinical practice.Aim: The goal of our study is to specify the value of basal GH level measurement 24 hours later after transsphenoidal surgery as postop...